Brightening ·

Moderate evidence

Arbutin

What is it?

Arbutin is a naturally occurring glycoside (a glycosylated form of hydroquinone), most often derived from bearberry and related plants, used in skincare as a tyrosinase-inhibiting brightening ingredient.

What does it do?

Comparative laboratory studies found arbutin inhibits human tyrosinase, but relatively weakly -- with a half-maximal inhibitory concentration in the millimolar range -- making it markedly less potent in vitro than newer agents like 4-n-butylresorcinol, though it remains a widely used, gentler option in brightening formulations.

Who may benefit?

  • May help with: Hyperpigmentation & Dark Marks

How to use

Typically formulated at around 1%.

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Sources

Important disclaimer

This page provides general skincare information and is not medical advice, diagnosis or treatment. Ingredient interactions and evidence summaries reflect published, cited sources — not a personal assessment of your skin. For medical skin conditions, rashes, pregnancy/lactation questions or persistent concerns, please consult a licensed dermatologist or HPCSA-registered practitioner.