Bromelain

What is it?

A proteolytic enzyme derived from pineapple stems, used in skincare for enzymatic exfoliation -- its best-documented topical medical use is actually in wound debridement rather than cosmetic exfoliation.

What does it do?

According to PubMed, proof-of-concept clinical studies of a topical bromelain-enriched enzymatic concentrate (originally developed and already used for burn-wound debridement) found it eradicated basal cell carcinoma lesions in the majority of 22 tumors treated, well tolerated with healing within 2-3 weeks -- real, if specialized, clinical evidence for bromelain's proteolytic/anti-inflammatory action, from a medical/oncology-debridement context rather than a cosmetic exfoliation efficacy trial.

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Sources

Effective Treatment of Basal Cell Carcinoma with a Topical Enzymatic Mixture Enriched in Bromelain

Important disclaimer

This page provides general skincare information and is not medical advice, diagnosis or treatment. Ingredient interactions and evidence summaries reflect published, cited sources — not a personal assessment of your skin. For medical skin conditions, rashes, pregnancy/lactation questions or persistent concerns, please consult a licensed dermatologist or HPCSA-registered practitioner.