Antioxidant ·

Limited evidence

Caffeine

What is it?

A naturally occurring xanthine alkaloid found in coffee, tea and guarana, used topically in skincare for its antioxidant and penetration-modifying properties.

What does it do?

Topical active readily absorbed through skin -- pharmaceutical-science studies confirm real percutaneous absorption and show it can be used as a marker/enhancer compound in penetration research; commonly included in eye creams and anti-redness/anti-cellulite formulations, though these specific cosmetic-efficacy claims have less direct clinical-trial support than its absorption behaviour.

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Sources

Important disclaimer

This page provides general skincare information and is not medical advice, diagnosis or treatment. Ingredient interactions and evidence summaries reflect published, cited sources — not a personal assessment of your skin. For medical skin conditions, rashes, pregnancy/lactation questions or persistent concerns, please consult a licensed dermatologist or HPCSA-registered practitioner.