Barrier & Lipid ·

Moderate evidence

Dimethicone

What is it?

A silicone-based occlusive ingredient that forms a breathable barrier film on skin, widely used as a skin protectant and in moisturizers.

What does it do?

According to PubMed, a randomized crossover trial in health care workers found dimethicone cream (compared with hydrocolloid dressing and N95-mask-alone conditions) significantly reduced adverse skin reactions from prolonged N95 mask wear, without interfering with mask seal integrity -- real clinical evidence for dimethicone's protective, barrier-forming function under mechanical/occlusive stress, a different use case from its more common role as a lightweight moisturizer emollient.

Local suppliers (Coming soon)

We're building a directory of South African suppliers and manufacturers who stock this ingredient — check back soon.

See how this fits your skin — try SKYNN AI, free

Sources

Important disclaimer

This page provides general skincare information and is not medical advice, diagnosis or treatment. Ingredient interactions and evidence summaries reflect published, cited sources — not a personal assessment of your skin. For medical skin conditions, rashes, pregnancy/lactation questions or persistent concerns, please consult a licensed dermatologist or HPCSA-registered practitioner.