Disodium Cocoamphodiacetate

What is it?

A mild, coconut-derived amphoteric surfactant commonly used in baby and sensitive-skin cleansers, often paired with harsher primary surfactants to soften their irritation potential.

What does it do?

According to PubMed, a 2010 patch-test study of 105 patients comparing 8 common cleanser surfactants found disodium cocoamphodiacetate was among the best-tolerated, alongside two mild anionic surfactants (sodium cocoyl glutamate and sodium lauroyl oat amino acids), causing neither irritant nor allergic reactions in any of the 105 tested patients (https://pubmed.ncbi.nlm.nih.gov/20920412/ -- no DOI listed for this article in PubMed).

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Sources

Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patients

Important disclaimer

This page provides general skincare information and is not medical advice, diagnosis or treatment. Ingredient interactions and evidence summaries reflect published, cited sources — not a personal assessment of your skin. For medical skin conditions, rashes, pregnancy/lactation questions or persistent concerns, please consult a licensed dermatologist or HPCSA-registered practitioner.