Probiotic ·

Moderate evidence

Live Lactobacillus Cultures

What is it?

Live Lactobacillus cultures are probiotic bacterial strains used topically to support the skin microbiome, with immunomodulatory, anti-inflammatory and antimicrobial properties.

What does it do?

Commonly used to help rebalance the skin microbiome and calm inflammation. A GRADE systematic review and meta-analysis of randomized controlled trials found Lactobacillus-based microbiome therapy effective for acne vulgaris with a favorable safety profile, and a separate randomized double-blind trial found Lactobacillus-derived postbiotics improved a chronic inflammatory skin condition.

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Sources

Important disclaimer

This page provides general skincare information and is not medical advice, diagnosis or treatment. Ingredient interactions and evidence summaries reflect published, cited sources — not a personal assessment of your skin. For medical skin conditions, rashes, pregnancy/lactation questions or persistent concerns, please consult a licensed dermatologist or HPCSA-registered practitioner.