Squalene (Plant-Derived)

INCI: Squalene

What is it?

A triterpene lipid naturally present in human skin-surface sebum, used topically as an emollient and antioxidant -- most commercial skincare instead uses the hydrogenated, more oxidatively stable form "Squalane" (a separate, not-yet-catalogued INCI entry).

What does it do?

According to PubMed, a review of squalene's biological and pharmacological activity in cosmetic dermatology documents real emollient, antioxidant, hydrating and some antitumor-activity evidence from in vitro and in vivo studies, and notes its established use in topical lipid emulsions and nanostructured lipid carriers.

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Sources

Biological and pharmacological activities of squalene and related compounds

Important disclaimer

This page provides general skincare information and is not medical advice, diagnosis or treatment. Ingredient interactions and evidence summaries reflect published, cited sources — not a personal assessment of your skin. For medical skin conditions, rashes, pregnancy/lactation questions or persistent concerns, please consult a licensed dermatologist or HPCSA-registered practitioner.