Peptide ·

Moderate evidence

Peptides

What is it?

Peptides are short chains of amino acids used in skincare to signal collagen production, deliver bioactive fragments, or otherwise support skin structure and anti-aging goals.

What does it do?

Commonly used to help support collagen production and improve signs of skin aging. A randomized double-blind controlled trial found a novel cyclized hexapeptide outperformed retinol on skin aging measures with better stability and permeability, and a separate split-face trial found a collagen-III multi-peptide serum improved outcomes when combined with collagen injection therapy for photoaging.

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Sources

Important disclaimer

This page provides general skincare information and is not medical advice, diagnosis or treatment. Ingredient interactions and evidence summaries reflect published, cited sources — not a personal assessment of your skin. For medical skin conditions, rashes, pregnancy/lactation questions or persistent concerns, please consult a licensed dermatologist or HPCSA-registered practitioner.