Optiphi · Serum

Active Retinol Serum 7.5 / 10

Name: Active Retinol Serum
Brand: Optiphi

Reviewed by Michael C.

A peptide-retinol rejuvenation serum built for clinician-guided regimens — solid actives at a professional price.

Efficacy8.0

Value for money6.5

Texture8.0

SA climate fit7.5

SkinLabs Promise — No Hype. Just Evidence.

The SkinLabs Promise

No hype, just evidence — this review is independently researched from publicly available information, ingredient analysis and editorial testing.

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Built around Active Retinol Serum — every other step is the highest-scoring, skin-type-matched product in our review set, not a fabricated or paid recommendation.

Estimated routine costR1895

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The full breakdown

A peptide-retinol rejuvenation serum built for clinician-guided regimens — solid actives at a professional price.

Ingredient breakdown

Retinol
Moderate evidence
Commonly used to help address visible signs of photoaging (fine lines, uneven texture, dullness) by promoting skin cell turnover and supporting collagen synthesis.
Peptides
Moderate evidence
Commonly used to help support collagen production and improve signs of skin aging. A randomized double-blind controlled trial found a novel cyclized hexapeptide outperformed retinol on skin aging measures with better stability and permeability, and a separate split-face trial found a collagen-III multi-peptide serum improved outcomes when combined with collagen injection therapy for photoaging.

Best suited to

Mature, Resilient

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